How could a patient who’s had a full/radical Prostatectomy years ago, show a high PSA level again?
Okay, we know that PSA (Prostate Specific Antigen) is produced by prostate gland cells (the epithelium) hence it is reasonable to think that the cells will continue to manufacture PSA even if they are in locations outside the prostate? Having said that, does an elevated level of PSA in a prostate cancer patient in remission and with full/radical Prostatectomy indicates the presence of a metastatic tumor somewhere? If NOT how and why could the PSA levels be so elevated in the above described patient? Your informed comments will be greatly appreciated – Thank You.
***guitargadfly – Thanks for your concern and your kind answer. I am not the one afflicted with this horrible disease, but an older and very dear friend of mine. He has already suffered tremendously because of it. And now him and his wife are all worried to pieces with his latest elevated PSA results.
Because PSA is specific for prostate, I’d be very concerned about recurrence or metastasis.
There could have been invasion of the tumour that was missed, or early, previously undetected metastasis at the time of surgery.
My best to your friend… good luck with a bad disease.
Following hormone therapy, the PSA may still increase. Managing this situation is very controversial. Learn about the various options and how to decide what to do.
Dr. Briers is Founder and General Director of Beta Ventures a publisher, congress organiser and business consulting firm providing information, journals, further training and services for clinical biologists and the diagnostic and medical industry.
In some men, the PSA may still rise after radiation therapy. Is this dangerous? Do all men need to be treated? Can those who are potentially in danger be identified and selectively treated. Learn the answers in the accompanying video.
New Prostate Cancer Procedure Being Tested in US Clinical Trials International HIFU
