A friend of mine, who is 56 years old, was just diagnosed with prostate cancer. He has a pretty advanced case, gleason grade 9 and I think a PSA under 10. His dad died of prostate cancer. The doctors are worried because a year ago, he was tested and had extremely low PSA levels, but now they are much higher. This could be a sign of aggression. They don’t know if it has spread yet. His doctor has recommended surgery in Seattle.
Has anyone gone through this? Can anyone tell me what the likelihood is that he will be OK?
Oh, just found out the PSA last year was 2 and now is 5.

The Gleason score "grades" tumors on the basis of how abnormal they look when the tissue is examined under a microscope. The more abnormal they look, the more likely they are to grow fast and to spread to other parts of the body. A grade of less than 4 generally means that cancer cells look similar to normal cells. Grades 5 to 7 fall under the intermediate range. Grades 8 to 10 indicate aggressive growth. survival rate is an average of 5 years.i would have a second opinion,and maybe some more tests such as a cat scan,bone scan(this shows what is called (hot spots) to show advancement and a biopsy to examine types.the grading can get complicated what you do need to ask is what his T-score is or TNM this tells basically if a primary Tumor Localized) n is for spread into lymph Nodes (regional)and M Metastatic into other bones(stage 4) or organs.then life expectancy is calculated for each stage. let me know what his Tscore is and email me with any other facts or test results. the best thing you can do is support your friend on his choices and through his recovery.

Prostate cancer is easily treatable IF caught early!!!

This info is incredibly important. Absolutely have a PSA test done if you are over 40, and repeat the test every year from then on. If it rises significantly, like a half point or more, repeat the test and if the increase persists, discuss with your physician about having a biopsy. If you catch prostate cancer early, it if very treatable. If you catch it late, it can kill you. Enough said.

My PSA in 1995 was 4.2 and my doctor gave me antibiotics to see if it would come down. It did and everytime my PSA went up, here came the antibiotics. Last year, I went on Medicare and my PSA was again 4.2. This doctor said it’s not high enough to worry about yet.

I changed insurance and doctors in January. When my PSA came back at 4.3 in February, my new doctor insisted I have a biopsy. This was done in a Urologists office with no drugs. I was relived when it was over. Now came the hard part, waiting for the results.

Out of all the cores they took, my cancer was in 85% of them. My Gleason score is 9 (4+5). The only scores worse than that is 9 (5+4) and 10 (5+5). I have a very aggressive form of prostate cancer. My only treatment is to have 42 extrernal beam radiation sessions over an eight and one-half week period. While they are burning my rectum, I’m also having hormone shots to block my testersone, that’s what makes you a man. In three months I’ll under go another biopsy, to see if I will need to have radioactive seeds implanted in what’s left of my prostate. At this point removal, for me, is not an option.

Removal is the desired treatment since removing the prostate cancels any worry of cancer if the cancer has not spread beyond the prostate. If it has, you must continue on with radiation. With the prostate gone your PSA will now be Zero.

As Larry, the Cable Guy says, "Get R Done"

Additional thoughts: I attended a seminar on Prostate cancer treatments to hear a doctor mention he had a 42 year old patient with a PSA of 2.5 and a Gleason score of 10. PSA isn’t always the answer, the Gleason score, can only be found with a biopsy, is the answer.

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Her is a second opinion:

PSA is measured by nanograms per millimeter of blood. Most men have under 4 nanograms. Anything higher can indicate prostate cancer.

According to the American Cancer Society, a PSA level between 4 and 10, indicates a 25% chance of it being prostate cancer. A PSA higher than 10, increases the chance of having prostate cancer to 50% and above.

There are several factors that can also elevate the PSA, such as:

•ejaculation (no ejaculation at least two days prior to test)

•PSA levels can naturally increase with age

•inflammation of the prostate gland

•non cancerous enlargement of the prostate

Also take into consideration that certain medications and herbal supplements can lower your PSA level falsely. It is important to let your physician know what meds you are taking before the test.

Take your pick. There really is no true number.

Tin
Mine is 2.1 I am 66 years old. Have benign prostrate hyperplasia . A swelling of the prostate. I take pills for it.. It works.

You don’t mention your husband’s age, PSA will also rise with age. Ask to go along to the urologist next time and ask him about your concerns. Sometimes I think that the only reason that married men live longer is that their wives worry about them and make them get needed medical care!